[Cardio-Oncology-Addressing Unmet Needs through Guidelines and Evidence Gaps].

With advancements in cancer treatment, the number of cancer survivors is increasing, underscoring the growing importance of cardio-oncology. For the safe and effective completion of cancer treatment, managing cardiovascular risk factors and cancer therapy-related cardiovascular complications is essential. Recently, several cardio-oncology clinical guidelines have been published both domestically and internationally. However, a significant evidence gap remains, as the majority of high-class recommendations are based on low-level supporting evidence. Additionally, the rapid advancements in both oncology and cardiology pose challenges in maintaining the relevance of guidelines. Therefore, interdisciplinary collaboration focused on the validity, feasibility, and sustainability of clinical practice guidelines is crucial for the future. Japan, as a super-aged society ahead of the rest of the world, could serve as a valuable source of real-world evidence, positioning itself as a global leader in education, clinical practice, and research in cardio-oncology.