Bouquet of flower calcification in renal tubular acidosis

Nephrocalcinosis, marked by calcium phosphate deposition in the kidneys, is often linked to distal renal tubular acidosis (dRTA). While typically driven by hypercalciuria, hyperphosphaturia can also promote crystal formation in alkaline urine. A 24-year-old female with recurrent fractures and hip pain presented with hypokalemia, metabolic acidosis, and hyperphosphaturia but without hypercalciuria. Imaging revealed medullary nephrocalcinosis and osteomalacia, secondary to dRTA. Potassium citrate improved her condition. This case emphasizes early recognition of dRTA to prevent renal and skeletal complications.

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Publication Details

Journal
QJM
Published
2025-05-15
DOI
https://doi.org/10.1093/qjmed/hcaf113
Primary Topic
Kidney Stones and Urolithiasis Treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Bouquet of flower calcification in renal tubular acidosis

Ayan Roy, Shaik Mohammad Tahaseen, Somdatta Giri, Shinjan Patra
QJM
Kidney Stones and Urolithiasis Treatments
article

Bouquet of flower calcification in renal tubular acidosis

Ayan Roy, Shaik Mohammad Tahaseen, Somdatta Giri, Shinjan Patra
article en

Abstract

Nephrocalcinosis, marked by calcium phosphate deposition in the kidneys, is often linked to distal renal tubular acidosis (dRTA). While typically driven by hypercalciuria, hyperphosphaturia can also promote crystal formation in alkaline urine. A 24-year-old female with recurrent fractures and hip pain presented with hypokalemia, metabolic acidosis, and hyperphosphaturia but without hypercalciuria. Imaging revealed medullary nephrocalcinosis and osteomalacia, secondary to dRTA. Potassium citrate improved her condition. This case emphasizes early recognition of dRTA to prevent renal and skeletal complications.

QJMVol. 118(11)
All India Institute of Medical Sciences Raipur (IN), All India Institute of Medical Sciences Bhopal (IN), All India Institute of Medical Sciences (IN), University of Kalyani (IN)
Zero hunger
Openalex Percentile: Top 80%
Kidney Stones and Urolithiasis Treatments
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