Quality of life 1 year after uterine artery embolization vs hysterectomy for symptomatic adenomyosis (<scp>QUESTA</scp> study)
Both UAE and hysterectomy significantly increased HRQOL for symptomatic adenomyosis. Neither non-inferiority nor inferiority of UAE could be established. One-year HRQOL scores were comparable; some secondary outcomes were in favor of hysterectomy. UAE is a valid less-invasive alternative to hysterectomy, with preservation of the uterus. Hysterectomy remains the treatment of choice for patients seeking a definite solution.
Authors
- Judith A.F. Huirne (ORCID: https://orcid.org/0000-0002-8248-2677)
- Marleen de Lange
- Lonneke S.F. Yo
- Carroll M. Tseng
- Erica A. Bakkum
- Annefleur M. de Bruijn (ORCID: https://orcid.org/0000-0001-8563-9660)
- Paul van Kesteren
- Jacques W.M. Maas (ORCID: https://orcid.org/0000-0003-1171-5418)
- Celine M. Radder (ORCID: https://orcid.org/0000-0001-7555-4073)
- Alexander Venmans
- Robert A. de Leeuw (ORCID: https://orcid.org/0000-0002-9344-7754)
- Han Kruimer
- S.F.P.J. Coppus (ORCID: https://orcid.org/0000-0001-6786-5824)
- Carla van Rijswijk (ORCID: https://orcid.org/0000-0002-7958-6926)
- Peggy M. A. J. Geomini (ORCID: https://orcid.org/0000-0002-1951-1076)
- Otto E. H. Elgersma
- Mark Arntz (ORCID: https://orcid.org/0000-0002-2402-7617)
- Annika Semmler
- Janet Kwee
- Jos W. R. Twisk (ORCID: https://orcid.org/0000-0001-9617-1020)
- Douwe Vos
- Marieke Smink
- Freek Groenman (ORCID: https://orcid.org/0000-0003-4532-4829)
- Marissa J. Harmsen (ORCID: https://orcid.org/0000-0003-3842-5023)
- Aloys F. J. Wüst
- Wouter J.K. Hehenkamp (ORCID: https://orcid.org/0000-0003-3678-7899)
- Gretel van Hoecke
- Jeroen van Bavel (ORCID: https://orcid.org/0000-0002-0915-989X)
- Lisa M. Trommelen (ORCID: https://orcid.org/0000-0002-9588-3154)
- Petra F. Janssen
- Armand Lamers
- Paul N.M. Lohle (ORCID: https://orcid.org/0000-0003-3323-3196)
- Iris van Rooij (ORCID: https://orcid.org/0000-0001-6520-4635)
- Velja Mijatovic (ORCID: https://orcid.org/0000-0002-0435-9921)
- Rutger J. Lely (ORCID: https://orcid.org/0000-0003-1741-9126)
- Frank Willem Jansen (ORCID: https://orcid.org/0000-0002-6192-3787)
- Anne Timmermans
- Joost G. A. M. Blomjous
- Huib A. A. M. van Vliet (ORCID: https://orcid.org/0000-0003-3709-9633)
- Laurens van Boven
- Andries R. H. Twijnstra
Institutions
- Loyola University Medical Center (US)
- Radboud University Nijmegen (NL)
- Leiden University Medical Center (NL)
- Catharina Ziekenhuis (NL)
- Radboud University Medical Center (NL)
- Albert Schweitzer Ziekenhuis (NL)
- OLVG (NL)
- Amphia Ziekenhuis (NL)
- Amsterdam Neuroscience (NL)
- Máxima Medisch Centrum (NL)
- Elisabeth-TweeSteden Ziekenhuis (NL)
- Ziekenhuis Groep Twente (NL)
- Amsterdam University Medical Centers (NL)
- Vrije Universiteit Amsterdam (NL)
- University of Amsterdam (NL)
Publication Details
- Journal
- Acta Obstetricia Et Gynecologica Scandinavica
- Published
- 2025-05-26
- DOI
- https://doi.org/10.1111/aogs.15165
- Citations
- 1
- Primary Topic
- Endometriosis Research and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 1.70
Funders
- Boston Scientific Corporation
- Merit Medical Systems