Racial ethnic variations in the cardiometabolic determinants and blood pressure of white matter hyperintensities among females—The HABS‐HD Study

Overall, there was a main effect of hypertension; however, in stratified analyses hypertension was significantly was associated with greater white matter hyperintensity (WMH) burden in non-Hispanic White females. Non-Hispanic Black females presented with a worse cardiometabolic profile, but this composite was not associated with WMH burden. There was a positive association with the risk composite in non-Hispanic White and Hispanic females. Systolic blood pressure and mean arterial pressure were associated with greater WMH in non-Hispanic Black females, highlighting differential blood pressure contributions to WMH burden.