Individual and combined walnut oil and blueberry attenuate lipopolysaccharide-induced neuroinflammation in rat microglia

BB and WO each reduced LPS-induced inflammation in microglia, but their combination was not more effective, suggesting no synergistic effect. This result suggests that they may work through similar mechanisms to attenuate inflammation in microglia. Overall, the reduction in neuroinflammation shows that the addition of BBs or walnuts to the diet may attenuate neuroinflammation linked to neurodegeneration.

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Publication Details

Journal
Nutritional Neuroscience
Published
2025-05-26
DOI
https://doi.org/10.1080/1028415x.2025.2509753
Primary Topic
Nuts composition and effects
Type
article
Field-Weighted Citation Impact
0.00

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article

Individual and combined walnut oil and blueberry attenuate lipopolysaccharide-induced neuroinflammation in rat microglia

Danielle S. Cahoon, Amanda N. Carey, Barbara Shukitt‐Hale, Derek R. Fisher
1 links
Nutritional Neuroscience
Nuts composition and effects
article

Individual and combined walnut oil and blueberry attenuate lipopolysaccharide-induced neuroinflammation in rat microglia

Danielle S. Cahoon, Amanda N. Carey, Barbara Shukitt‐Hale, Derek R. Fisher
article en

Abstract

BB and WO each reduced LPS-induced inflammation in microglia, but their combination was not more effective, suggesting no synergistic effect. This result suggests that they may work through similar mechanisms to attenuate inflammation in microglia. Overall, the reduction in neuroinflammation shows that the addition of BBs or walnuts to the diet may attenuate neuroinflammation linked to neurodegeneration.

Nutritional NeuroscienceVol. 28(11)
Tufts University (US), Simmons University (US)
Agricultural Research Service
Zero hunger
Openalex Percentile: Top 86%
Nuts composition and effects
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