Individual and combined walnut oil and blueberry attenuate lipopolysaccharide-induced neuroinflammation in rat microglia
BB and WO each reduced LPS-induced inflammation in microglia, but their combination was not more effective, suggesting no synergistic effect. This result suggests that they may work through similar mechanisms to attenuate inflammation in microglia. Overall, the reduction in neuroinflammation shows that the addition of BBs or walnuts to the diet may attenuate neuroinflammation linked to neurodegeneration.
Authors
- Danielle S. Cahoon (ORCID: https://orcid.org/0000-0002-3243-1804)
- Amanda N. Carey (ORCID: https://orcid.org/0000-0002-8453-9884)
- Barbara Shukitt‐Hale (ORCID: https://orcid.org/0000-0002-3810-1910)
- Derek R. Fisher
Institutions
- Tufts University (US)
- Simmons University (US)
Publication Details
- Journal
- Nutritional Neuroscience
- Published
- 2025-05-26
- DOI
- https://doi.org/10.1080/1028415x.2025.2509753
- Primary Topic
- Nuts composition and effects
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Agricultural Research Service