Comparison of the clinical characteristics of children with Silver–Russell syndrome genetically confirmed or not and their response to growth hormone therapy: a national multicenter study
11p15 LOM was the most common genetic disorder in children with SRS in our case series. Gastroenterological problems and neurologic complications were observed frequently in these cases. Central precocious puberty was more commonly observed compared to the general population. The duration of treatment was the most critical factor in the success of GH therapy.
Authors
- Şükrü Hatun (ORCID: https://orcid.org/0000-0003-1633-9570)
- Şükran Poyrazoğlu (ORCID: https://orcid.org/0000-0001-6806-9678)
- Elif Eviz (ORCID: https://orcid.org/0000-0002-8889-6811)
- Atilla Çayır (ORCID: https://orcid.org/0000-0001-9776-555X)
- Hasan Karakaş (ORCID: https://orcid.org/0000-0003-2282-2606)
- Semra Çeti̇nkaya (ORCID: https://orcid.org/0000-0003-3974-2872)
- Ahmet Uçar (ORCID: https://orcid.org/0000-0001-8144-8437)
- İlker Tolga Özgen (ORCID: https://orcid.org/0000-0001-6592-9652)
- Tuğçe Kandemir (ORCID: https://orcid.org/0000-0003-1561-2862)
- Olcay Evliyaoğlu (ORCID: https://orcid.org/0000-0003-4851-8637)
- Senem Esen (ORCID: https://orcid.org/0000-0003-2381-6726)
- Şükran Darcan (ORCID: https://orcid.org/0000-0002-1330-6397)
- Zeynep Şıklar (ORCID: https://orcid.org/0000-0003-0921-2694)
- Merih Berberoğlu (ORCID: https://orcid.org/0000-0003-3102-0242)
- Feyza Darendelıler (ORCID: https://orcid.org/0000-0003-4786-0780)
- Gül Yeşiltepe Mutlu (ORCID: https://orcid.org/0000-0003-3919-7763)
- Leyla Akın (ORCID: https://orcid.org/0000-0002-8071-426X)
- Korcan Demir (ORCID: https://orcid.org/0000-0002-8334-2422)
- Bahar Özcabı (ORCID: https://orcid.org/0000-0002-1089-9326)
- Gözde Akın Kağızmanlı (ORCID: https://orcid.org/0000-0002-6158-9002)
- Sema Nilay Abseyi (ORCID: https://orcid.org/0000-0002-0303-6274)
- Hatice Nursoy (ORCID: https://orcid.org/0000-0003-3436-9239)
- Semra Bahar (ORCID: https://orcid.org/0000-0002-7113-9646)
- Melek Yıldız (ORCID: https://orcid.org/0000-0002-6603-2983)
- Zümrüt Kocabey Sütçü (ORCID: https://orcid.org/0000-0001-7335-1272)
- Murat Aydın (ORCID: https://orcid.org/0000-0001-7374-229X)
- Nursel Muratoğlu Şahin (ORCID: https://orcid.org/0000-0002-8215-0146)
- Deniz Özalp Kızılay (ORCID: https://orcid.org/0000-0003-4529-4404)
Institutions
- Bursa Uludağ Üni̇versi̇tesi̇ (TR)
- Koç University (TR)
- Ankara University (TR)
- University of Health Science (KH)
- Dokuz Eylül University (TR)
- Ondokuz Mayıs University (TR)
- Bezmiâlem Vakıf Üniversitesi (TR)
- Acıbadem University (TR)
- Ege University (TR)
- Biruni University (TR)
- Istanbul Metropolitan Municipality (TR)
- Istanbul University-Cerrahpaşa (TR)
- Erzurum Regional Training and Research Hospital (TR)
- Sağlık Bilimleri Üniversitesi (TR)
- İstanbul Başakşehir Çam ve Sakura Şehir Hastanesi
- Istanbul University (TR)
- University of Health Sciences Antigua (AG)
Publication Details
- Journal
- Journal of Pediatric Endocrinology and Metabolism
- Published
- 2025-05-27
- DOI
- https://doi.org/10.1515/jpem-2024-0587
- Primary Topic
- Genetic Syndromes and Imprinting
- Type
- article
- Field-Weighted Citation Impact
- 0.00