Hyperlipidemia Triggers Trophoblast Cell Dysfunction and Preeclampsia via the AMPK/GATA3/FTL Pathway
This study revealed that high lipid levels contribute to preeclampsia by downregulating FTL through the AMPK-GATA3 pathway, highlighting potential therapeutic targets for preeclampsia management.
Authors
- Jian Wang (ORCID: https://orcid.org/0009-0008-2021-570X)
- Yiling Wei (ORCID: https://orcid.org/0009-0004-7821-4989)
- Ka Cheuk Yip (ORCID: https://orcid.org/0000-0001-9979-9104)
- Lei Guo (ORCID: https://orcid.org/0000-0003-3462-4033)
- Ruiman Li (ORCID: https://orcid.org/0000-0003-1239-7968)
- Jiachun Wei (ORCID: https://orcid.org/0009-0004-8410-0988)
- Yudie Gao
- Feng Gao (ORCID: https://orcid.org/0000-0001-8903-0203)
- Xiufang Wang (ORCID: https://orcid.org/0000-0002-4223-8004)
- Qiao Zhang (ORCID: https://orcid.org/0000-0002-6415-7299)
- Hanhui Nie
- Xiaman Huang
Institutions
- Jinan University (CN)
- First Affiliated Hospital of Jinan University (CN)
Publication Details
- Journal
- Hypertension
- Published
- 2025-05-27
- DOI
- https://doi.org/10.1161/hypertensionaha.125.24839
- Citations
- 2
- Primary Topic
- Pregnancy and preeclampsia studies
- Type
- article
- Field-Weighted Citation Impact
- 4.11