Synchronous Sigmoid Colon and Small Bowel Adenocarcinomas: A Rare Case of Dual Primary Malignancies Presenting With Acute Bowel Obstruction

Synchronous colorectal and small bowel adenocarcinomas are exceptionally rare. This case report presents a 65-year-old male patient with acute bowel obstruction who underwent an emergency laparotomy. Intraoperative findings revealed synchronous sigmoid colon and small bowel tumors with peritoneal metastases. The patient underwent sigmoidectomy, small bowel resection, and metastasectomy. Histopathology confirmed two distinct primary adenocarcinomas. Postoperative management included KRAS mutation-guided chemotherapy. At the two-year follow-up, the patient remained disease-free. This case highlights the importance of thorough intraoperative exploration in emergency presentations and demonstrates the potential for favorable outcomes with aggressive multimodal treatment in synchronous gastrointestinal malignancies.

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Journal
Cureus
Published
2025-05-27
DOI
https://doi.org/10.7759/cureus.84877
Primary Topic
Multiple and Secondary Primary Cancers
Type
article
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article

Synchronous Sigmoid Colon and Small Bowel Adenocarcinomas: A Rare Case of Dual Primary Malignancies Presenting With Acute Bowel Obstruction

Shaher Abbarah, Beshr Mosa Basha, Yusuf Kaaki, Naji Fliti
Cureus
Multiple and Secondary Primary Cancers
article

Synchronous Sigmoid Colon and Small Bowel Adenocarcinomas: A Rare Case of Dual Primary Malignancies Presenting With Acute Bowel Obstruction

Shaher Abbarah, Beshr Mosa Basha, Yusuf Kaaki, Naji Fliti
article en

Abstract

Synchronous colorectal and small bowel adenocarcinomas are exceptionally rare. This case report presents a 65-year-old male patient with acute bowel obstruction who underwent an emergency laparotomy. Intraoperative findings revealed synchronous sigmoid colon and small bowel tumors with peritoneal metastases. The patient underwent sigmoidectomy, small bowel resection, and metastasectomy. Histopathology confirmed two distinct primary adenocarcinomas. Postoperative management included KRAS mutation-guided chemotherapy. At the two-year follow-up, the patient remained disease-free. This case highlights the importance of thorough intraoperative exploration in emergency presentations and demonstrates the potential for favorable outcomes with aggressive multimodal treatment in synchronous gastrointestinal malignancies.

CureusVol. 17(5)
Alfaisal University (SA), Saad Specialist Hospital (SA), Sulaiman Al Rajhi Colleges (SA)
Good health and well-being
Openalex Percentile: Top 83%
Multiple and Secondary Primary Cancers
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