Investigating the Genetic Basis of the Influence of Adiposity on Psoriasis: A Cross-Sectional Study in a Large United Kingdom Population–Based Biobank
Psoriasis is a chronic inflammatory skin disease that has a substantial associated global public health burden (Griffiths et al, 2021). Adiposity is prevalent among individuals with psoriasis, particularly those with more severe disease, and evidence suggests a risk-increasing causal relationship between adiposity and psoriasis. First, increasing body mass index, waist circumference, and waist-to-hip ratio have been shown to be associated with increased psoriasis risk in large population-based studies (Snekvik et al, 2017).
Authors
- Nick Dand (ORCID: https://orcid.org/0000-0002-1805-6278)
- Ashley Budu‐Aggrey (ORCID: https://orcid.org/0000-0002-8911-2492)
- Ravi Ramessur (ORCID: https://orcid.org/0000-0003-4599-9455)
- Michael A. Simpson (ORCID: https://orcid.org/0000-0002-8539-8753)
- Jake Saklatvala (ORCID: https://orcid.org/0000-0003-0836-4928)
- Satveer K. Mahil (ORCID: https://orcid.org/0000-0003-4692-3794)
- Juliet N. Barker (ORCID: https://orcid.org/0000-0002-9030-183X)
- Laurent F. Thomas (ORCID: https://orcid.org/0000-0003-0548-2486)
- Mari Løset (ORCID: https://orcid.org/0000-0003-3736-6551)
- Catherine Smith (ORCID: https://orcid.org/0000-0001-9918-1144)
Institutions
- King's College London (GB)
- Norwegian University of Science and Technology (NO)
- University of Bristol (GB)
- St Olav's University Hospital (NO)
- King's College School (GB)
Publication Details
- Journal
- Journal of Investigative Dermatology
- Published
- 2025-05-27
- DOI
- https://doi.org/10.1016/j.jid.2025.03.024
- Citations
- 4
- Primary Topic
- Psoriasis: Treatment and Pathogenesis
- Type
- article
- Field-Weighted Citation Impact
- 3.19
Funders
- Norges Teknisk-Naturvitenskapelige Universitet
- European Federation of Pharmaceutical Industries and Associations
- Innovative Health Initiative
- National Institute for Health and Care Research
- European Commission
- University of Bristol
- King's Health Partners
- St. Olavs Hospital Universitetssykehuset i Trondheim
- Medical Research Council
- Faculty of Medicine and Health, University of Sydney