Steady-state Dirichlet approximation of the Wright-Fisher model using the prelimit generator comparison approach of Stein’s method

Abstract The Wright–Fisher model, originating in Wright (1931) is one of the canonical probabilistic models used in mathematical population genetics to study how genetic type frequencies evolve in time. In this paper we bound the rate of convergence of the stationary distribution for a finite population Wright–Fisher Markov chain with parent-independent mutation to the Dirichlet distribution. Our result improves the rate of convergence established in Gan et al. (2017) from $\mathrm{O}(1/\sqrt{N})$ to $\mathrm{O}(1/N)$ . The results are derived using Stein’s method, in particular, the prelimit generator comparison method.

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Publication Details

Journal
Advances in Applied Probability
Published
2025-05-27
DOI
https://doi.org/10.1017/apr.2025.13
Primary Topic
Theoretical and Computational Physics
Type
article
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article

Steady-state Dirichlet approximation of the Wright-Fisher model using the prelimit generator comparison approach of Stein’s method

Han L. Gan, Anton Braverman
Advances in Applied Probability
Theoretical and Computational Physics
article

Steady-state Dirichlet approximation of the Wright-Fisher model using the prelimit generator comparison approach of Stein’s method

Han L. Gan, Anton Braverman
article en

Abstract

Abstract The Wright–Fisher model, originating in Wright (1931) is one of the canonical probabilistic models used in mathematical population genetics to study how genetic type frequencies evolve in time. In this paper we bound the rate of convergence of the stationary distribution for a finite population Wright–Fisher Markov chain with parent-independent mutation to the Dirichlet distribution. Our result improves the rate of convergence established in Gan et al. (2017) from $\mathrm{O}(1/\sqrt{N})$ to $\mathrm{O}(1/N)$ . The results are derived using Stein’s method, in particular, the prelimit generator comparison method.

Advances in Applied ProbabilityVol. 57(4)
University of Waikato (NZ)
Openalex Percentile: Top 93%
Theoretical and Computational Physics
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