New-onset type 2 diabetes mellitus complicated by diabetic ketoacidosis: a sentinel presentation of advanced pancreatic adenocarcinoma

Unexplained weight loss alongside newly-identified type 2 DM warrants thorough evaluation for occult malignancy. Elevated CA19-9 and CEA in the context of new-onset diabetes should raise suspicion for pancreatic malignancy. DKA may rarely serve as the initial manifestation of pancreatic cancer in newly-identified type 2 DM cases, necessitating a high index of clinical suspicion.