Bone filler and adhesive at the same time: in-vitro analysis in a porcine fracture model
This study presents a breakthrough approach using a bone cement as both a bone adhesive and a filler at the same time. The adhesive and drillable magnesium phosphate cement proved to be a versatile solution featuring a new surgical method in which the fracture was anatomically reduced using only the cement. Furthermore, with this new technique, the cement demonstrated comparable, if not slightly superior, biomechanical stability in the porcine tibial split depression fracture model compared to the current standard of surgical treatment using primary plate osteosynthesis and a commercial hydroxyapatite cement.
Authors
- Martin C. Jordan (ORCID: https://orcid.org/0000-0003-4356-0676)
- Stefanie Hoelscher‐Doht (ORCID: https://orcid.org/0000-0002-5294-8958)
- Uwe Gbureck (ORCID: https://orcid.org/0000-0002-2584-4176)
- Rainer H. Meffert (ORCID: https://orcid.org/0000-0002-6667-3262)
- Philipp Heilig (ORCID: https://orcid.org/0000-0003-3275-9874)
- Maximilian Heilig (ORCID: https://orcid.org/0000-0002-6286-5144)
- Nicola Zufall
- Lea Hüls
Institutions
- Universitätsmedizin Greifswald (DE)
- Universitätsklinikum Würzburg (DE)
- Berufsgenossenschaftliche Unfallklinik Frankfurt am Main (DE)
Publication Details
- Journal
- BMC Musculoskeletal Disorders
- Published
- 2025-05-27
- DOI
- https://doi.org/10.1186/s12891-025-08773-y
- Primary Topic
- Bone Tissue Engineering Materials
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Deutsche Forschungsgemeinschaft