Polyangiitis overlap syndrome is a high-risk clinical phenotype for relapse: Case series from the KEIO-vasculitis cohort
Polyangiitis overlap syndrome represents a high-risk phenotype for relapse, driven by AAV activity. Our findings suggest that IL-6 receptor blockade is a potential therapeutic option, highlighting the need for further research to establish optimal maintenance strategies in this complex disease entity.
Authors
- Jun Kikuchi (ORCID: https://orcid.org/0000-0002-6809-394X)
- Hiroshi Takei (ORCID: https://orcid.org/0000-0001-5167-0715)
- Kanako Shimanuki (ORCID: https://orcid.org/0009-0006-0001-1078)
- Koji Suzuki (ORCID: https://orcid.org/0000-0003-1358-7069)
- Koichi Saito (ORCID: https://orcid.org/0000-0001-6497-5286)
- Yasushi Kondo (ORCID: https://orcid.org/0000-0002-1566-2088)
- Mitsuhiro Akiyama (ORCID: https://orcid.org/0000-0001-5075-8977)
- Yuki Imai (ORCID: https://orcid.org/0000-0003-0729-9810)
- Yuko Kaneko (ORCID: https://orcid.org/0000-0003-2646-5765)
- Hiroki Tabata
Institutions
- Keio University (JP)
Publication Details
- Journal
- Modern Rheumatology
- Published
- 2025-05-27
- DOI
- https://doi.org/10.1093/mr/roaf041
- Primary Topic
- Vasculitis and related conditions
- Type
- article
- Field-Weighted Citation Impact
- 0.00