Intra-arterial hepatic chemotherapy in metastatic colorectal cancer: differences between oxaliplatin-naive versus oxaliplatin-pretreated patients

Oxaliplatin use as an intra-arterial hepatic infusion is feasible and efficient after previous systemic oxaliplatin; it showed significant response rates without increased toxicities. It can provide alternative treatments and spare late-setting drugs such as regorafenib and tipiracil-trifluridine for a further palliative intent treatment.

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Publication Details

Journal
ESMO Gastrointestinal Oncology
Published
2025-05-27
DOI
https://doi.org/10.1016/j.esmogo.2025.100173
Primary Topic
Hepatocellular Carcinoma Treatment and Prognosis
Type
article
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article

Intra-arterial hepatic chemotherapy in metastatic colorectal cancer: differences between oxaliplatin-naive versus oxaliplatin-pretreated patients

Thierry de Baère, David Malka, E Rawadi, C. Smolenschi et al.
ESMO Gastrointestinal Oncology
Hepatocellular Carcinoma Treatment and Prognosis
article

Intra-arterial hepatic chemotherapy in metastatic colorectal cancer: differences between oxaliplatin-naive versus oxaliplatin-pretreated patients

Thierry de Baère, David Malka, E Rawadi, C. Smolenschi, Luisa Pierotti, Maximiliano Gelli, Marine Valéry, Alina Fuerea, Lambros Tselikas, Baptiste Bonnet, T. Pudlarz, Alice Boilève, Michel Ducreux, Antoine Hollebecque, Elena Fernandez-De-Sevilla, A. Tarabay, V. Boige
article en

Abstract

Oxaliplatin use as an intra-arterial hepatic infusion is feasible and efficient after previous systemic oxaliplatin; it showed significant response rates without increased toxicities. It can provide alternative treatments and spare late-setting drugs such as regorafenib and tipiracil-trifluridine for a further palliative intent treatment.

ESMO Gastrointestinal OncologyVol. 8
Inserm (FR), Université Paris-Saclay (FR), Institut Gustave Roussy (FR), Institute Mutualiste Montsouris (FR)
Good health and well-being
Openalex Percentile: Top 83%
Hepatocellular Carcinoma Treatment and Prognosis
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Intra-arterial hepatic chemotherapy in metastatic colorectal cancer: differences between oxaliplatin-naive versus oxaliplatin-pretreated patients — Thierry de Baère, David Malka, et al. · ESMO Gastrointestinal Oncology (2025) | TGRS Research Map | TGRS