Genetic surveillance reveals low but sustained malaria transmission with clonal replacement in Sao Tome and Principe
These findings highlight the need to prioritize several interventions, such as targeted interventions against transmission hotspots, reactive case detection, and strategies to reduce the introduction of new parasites into this island nation as it approaches elimination. This study also serves as a case study for implementing genetic surveillance in a low transmission setting.
Authors
- Ronalg Mendes Costa d’ Assunção Carvalho
- Ying-An Chen (ORCID: https://orcid.org/0000-0002-7936-1313)
- Daniel García-Ruíz
- Cheng‐Sheng Lee (ORCID: https://orcid.org/0000-0002-0765-2410)
- Peng-Yin Ng
- Bryan Greenhouse (ORCID: https://orcid.org/0000-0003-0287-9111)
- Brian A. Palmer (ORCID: https://orcid.org/0000-0001-5032-4773)
- Lien-Fen Tseng
- Aaron Elliot
- Hsiao‐Han Chang (ORCID: https://orcid.org/0000-0001-8016-1530)
- Kun‐Hsien Tsai (ORCID: https://orcid.org/0000-0002-6154-113X)
Institutions
- National Taiwan University (TW)
- University of California, San Francisco (US)
- National Tsing Hua University (TW)
- Centro Nacional de Endemias (ST)
- Institute of Statistical Science, Academia Sinica (TW)
Publication Details
- Journal
- Communications Medicine
- Published
- 2025-05-27
- DOI
- https://doi.org/10.1038/s43856-025-00905-8
- Citations
- 2
- Primary Topic
- Malaria Research and Control
- Type
- article
- Field-Weighted Citation Impact
- 3.76
Funders
- Ministry of Science and Technology, Taiwan
- National Science and Technology Council
- National Institutes of Health
- University of California, San Francisco
- National Institute of Allergy and Infectious Diseases