Pigmented skin lesions with atypical histopathology indicating a diagnosis of multiple metastases of melanoma: A case report

The present study reports on the case of a middle-aged female patient who presented with a rapidly progressing pigmented skin lesion on the periphery, combined with multiple intracranial, pulmonary, hepatic and skeletal malignancies. The case was not clear in terms of histopathological manifestations and other aspects, which made the diagnosis of melanoma difficult. The present case details the challenges in the diagnostic process, as well as the importance of multidisciplinary comprehensive diagnosis and treatment, aiming to provide a reference for clinicians when dealing with similar complex pigmented skin lesions.