Aflatoxin B <sub>1</sub> Instigated Redox Imbalance is Accompanied by Amplified Indoleamine 2,3-Dioxygenase/tryptophan Catabolism in the Spleen and Erythrocyte of Male Wistar Rats: Protective Influence of Dietary Rutin
The activities/expression of immunosuppressive indoleamine 2, 3-dioxygenase is mostly regulated by inflammation and oxidative stress. This study provides new insights into the mechanisms underlying the modulation of immunotoxicity of AFB1 by dietary rutin.
Authors
- Olusanya Olasehinde (ORCID: https://orcid.org/0000-0003-0480-5634)
- Jacinta Nkechi Obimma
- Azubuike Peter Ebokaiwe (ORCID: https://orcid.org/0000-0003-2826-4844)
- Euslar Nnenna Onu (ORCID: https://orcid.org/0000-0002-7107-3296)
- Doris Olachi Alilonu (ORCID: https://orcid.org/0000-0002-4365-5715)
- C.U. Eze (ORCID: https://orcid.org/0000-0002-4944-445X)
- Okoro Nworie
Institutions
- University of Nigeria (NG)
- Funai Electric (Japan) (JP)
- University of Science and Technology of Benin (BJ)
- University of Benin (NG)
- Ebonyi State University (NG)
Publication Details
- Journal
- Immunological Investigations
- Published
- 2025-05-27
- DOI
- https://doi.org/10.1080/08820139.2025.2503171
- Primary Topic
- Tryptophan and brain disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00