Establishing the ground truth for keratoconus progression: combining repeated measures and adapting precision limits to disease severity in corneal tomography
MS-39 measurement precision is not significantly influenced by the operator. Consecutive repeated measures and adaptive thresholds for observed change in key tomographic parameters based on device specific precision limits tailored to disease severity are necessary for accurate classification of progression.
Authors
- Siyin Liu (ORCID: https://orcid.org/0000-0003-2684-4212)
- Bruce Allan (ORCID: https://orcid.org/0000-0002-8503-4482)
- Sri Gore (ORCID: https://orcid.org/0000-0002-1645-4993)
- Shafi Balal (ORCID: https://orcid.org/0000-0001-7683-2741)
- Pádraig J. Mulholland (ORCID: https://orcid.org/0000-0001-5166-0592)
- Marcello Leucci (ORCID: https://orcid.org/0000-0002-3998-6415)
- Yijun Cai (ORCID: https://orcid.org/0000-0003-3609-5163)
- Nikolas Pontikos (ORCID: https://orcid.org/0000-0003-1782-4711)
- Lynn Kandakji (ORCID: https://orcid.org/0000-0003-2947-6232)
Institutions
- Moorfields Eye Hospital (GB)
- University College London (GB)
- Inholland University of Applied Sciences (NL)
Publication Details
- Journal
- Journal of Cataract & Refractive Surgery
- Published
- 2025-05-27
- DOI
- https://doi.org/10.1097/j.jcrs.0000000000001692
- Citations
- 1
- Primary Topic
- Corneal surgery and disorders
- Type
- article
- Field-Weighted Citation Impact
- 1.36
Funders
- National Institute for Health and Care Research
- University College London
- Moorfields Eye Charity
- Medical Research Council