Chitosan Microspheres as a Delivery System for Nasal Insufflation

Chitosan, a naturally occurring polymer, has gained significant attention in recent years due to its useful qualities as a biomaterial.Its biodegradability, biocompatibility, and non-toxicity make it an ideal candidate for various biomedical applications.Chitosan microspheres have been extensively researched for their potential in drug delivery systems, including oral, nasal, ocular, vaginal, buccal, and parenteral routes.These microspheres can be prepared using various methods, including emulsification-crosslinking, ionotropic gelation, and spray drying.The properties of chitosan microspheres, such as particle size, charge, and loading capacity, can be tailored to suit specific applications.Chitosan has also been explored as a vaccine delivery system and gene delivery vector.Its ability to enhance immune responses and facilitate gene expression makes it a promising tool in the development of novel vaccines and gene therapies.