Bactericidal and Bioactive Ceramic Scaffold

Infections caused by bacteria are among the main factors for the rejection of materials used in implants. Ceramic scaffolds containing silver have been shown to be bioactive and bactericidal for different strains of bacteria. In this work, glasses containing silver were synthesized by the sol-gel method to obtain scaffolds. Bands were observed in the 1200–930 cm-1 region that can be attributed to Si–O–Si bonds, but also bands of overlapping phosphate groups, bands at 490 cm-1 of Si–O–NBO, Si–O-Zn, and diffraction peaks corresponding to the hydroxyapatite phase. Bioactivity tests in the presence of the body fluid simulating solution (SBF) and antibacterial activity tests indicate that the glass and scaffolds are bioactive and bactericidal.

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Publication Details

Journal
Orbital - The Electronic Journal of Chemistry
Published
2025-05-17
DOI
https://doi.org/10.17807/orbital.v17i2.20255
Primary Topic
Bone Tissue Engineering Materials
Type
article
Field-Weighted Citation Impact
0.00

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article

Bactericidal and Bioactive Ceramic Scaffold

Sílvia Denofre de Campos, C. Oliveira, Élvio Antônio de Campos, Juliana Cheleski Wiggers et al.
Orbital - The Electronic Journal of Chemistry
Bone Tissue Engineering Materials
article

Bactericidal and Bioactive Ceramic Scaffold

Sílvia Denofre de Campos, C. Oliveira, Élvio Antônio de Campos, Juliana Cheleski Wiggers, Gabrieli Andressa De Campos
article en

Abstract

Infections caused by bacteria are among the main factors for the rejection of materials used in implants. Ceramic scaffolds containing silver have been shown to be bioactive and bactericidal for different strains of bacteria. In this work, glasses containing silver were synthesized by the sol-gel method to obtain scaffolds. Bands were observed in the 1200–930 cm-1 region that can be attributed to Si–O–Si bonds, but also bands of overlapping phosphate groups, bands at 490 cm-1 of Si–O–NBO, Si–O-Zn, and diffraction peaks corresponding to the hydroxyapatite phase. Bioactivity tests in the presence of the body fluid simulating solution (SBF) and antibacterial activity tests indicate that the glass and scaffolds are bioactive and bactericidal.

Orbital - The Electronic Journal of Chemistry
Universidade Estadual do Oeste do Paraná (BR), Universidade Estadual do Paraná (BR)
Fundacion Araucaria, Conselho Nacional de Desenvolvimento Científico e Tecnológico
Openalex Percentile: Top 89%
Bone Tissue Engineering Materials
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Bactericidal and Bioactive Ceramic Scaffold — Sílvia Denofre de Campos, C. Oliveira, et al. · Orbital - The Electronic Journal of Chemistry (2025) | TGRS Research Map | TGRS