Effects of rotigotine on sleep in Parkinson’s disease patients: a Parkinson’s KinetiGraph study
Rotigotine improved sleep in patients with a baseline PDSS-2 ≥ 18 and in DA-naïve patients, but not in the whole study group. Additionally, rotigotine seemed to improve motor function and quality of life. PTI<sub>D</sub> improved with treatment. Whether the improved PTI<sub>D</sub> reflects a positive impact on daytime sleepiness or just improved mobility and to what extent PKG nighttime scores accurately represent sleep variables remains to be investigated in further studies.
Authors
- Per Odin (ORCID: https://orcid.org/0000-0002-0756-7478)
- Filip Bergquist (ORCID: https://orcid.org/0000-0002-3437-0267)
- Nil Dizdar (ORCID: https://orcid.org/0000-0002-9556-6984)
- Sotirios Grigoriou (ORCID: https://orcid.org/0000-0003-4951-6123)
- Malcolm Horne (ORCID: https://orcid.org/0000-0001-9427-2100)
- Carin Janz (ORCID: https://orcid.org/0000-0002-0394-378X)
Institutions
- Linköping University (SE)
- The University of Melbourne (AU)
- Lund University (SE)
- Sahlgrenska University Hospital (SE)
- St Vincent's Hospital Melbourne (AU)
- Skåne University Hospital (SE)
- University of Gothenburg (SE)
Publication Details
- Journal
- Frontiers in Neurology
- Published
- 2025-05-27
- DOI
- https://doi.org/10.3389/fneur.2025.1591537
- Citations
- 1
- Primary Topic
- Parkinson's Disease Mechanisms and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.39
Funders
- Lunds Universitet
- Skånes universitetssjukhus
- Parkinsonfonden