Our Experience Anesthetic and Surgical Approach of Debulking Procedures in Ovarian Cancer

Objective: We aimed to determine the rescue approach of anesthesiologists and discussed operations of debulking procedures in Ovarian Cancer (CA) and survey, in this study. Background: Most patients with ovarian cancer usually relapse during the first 5 years. Overall life expectancy is less than 50 % for 5 years, depending on the stage of the disease. Therefore, we follow the patients with an interval of 3-4 months for 5 years after the end of the operative treatment. Recurrent ovarian cancer diseases have the chance to be treated with surgery and different chemotherapy protocols. Materiel and Methods: This clinical study aimed to evaluate the approaches to cytoreductive surgery in our reference center. We only included studies that defined optimal cytoreduction as surgery leading to residual tumors with a maximum diameter of any threshold up to 2 cm. Patients of 2008 - 2018 operated from cytoreductive over carcinoma were retrospectively evaluated. This study includes perioperative clinical management, preoperative approach, fluid and blood management, prevention, and treatment of major complications in women of 2187 seconder operated ovarian CA. Results: Postoperative hyponatremia and anemia were detected. The fact that Ca 125 does not return to the target value after surgery supports the idea that surgery alone is insufficient in ovarian cancers. However, when the tumor burden decreases, the value of Ca 125 in the blood also decreases. Conclusion: In our study, we showed with statistical analysis the importance of monitoring the debulking operations in preoperative, intraoperative and postoperative periods and the effect of the procedures on the mortality.