Hormonal Therapy of Menopause and Mental Health

During the menopausal transition, which begins 4 to 6 years prior to stopping menstruation, women at this stage experience progressive changes in ovarian activity and physiological impairment of hypothalamic-pituitary-ovarian axis function associated with fluctuations in levels. hormonal; where they can suffer symptoms related to menopause such as vasomotor symptoms, sleep disorders, mood changes, memory problems and genitourinary syndrome of menopause. Neurological symptoms such as sleep disturbance and mood swings are the most important discomfort in the transition to menopause, which impacts quality of life, productivity and physical health. A review of the associations between menopause and/or hormone levels with sleep problems, mood and reduced cognitive performance is performed. During the transition to menopause, women experience dramatic fluctuations in the levels of sex hormones such as estradiol, progesterone, and androgens, responsible for changes in behavior, cognition, mood, and sleep.