Uncommon <scp><i>RHD</i></scp> variants and an unconventional <scp><i>RHCE</i></scp> hybrid allele with D epitope expression in blood donors from northwestern Croatia
This study reports the DEL phenotype of RHD*DEL44 expression. The hybrid allele RHCE*D(1)-CE was described previously, but here we illustrate the presence of D epitope(s) in a donor with homozygous RHD deletion. Weak D type 40 haplotype association was elucidated. Blood donor molecular Rh testing can prevent the immunization of genuine D-negative patients by D-positive units that reacted negatively in routine serological testing.
Authors
- Mirela Raos (ORCID: https://orcid.org/0000-0001-6588-7886)
- Koraljka Gojčeta
- Gordana Jaklin
- Branka Golubić‐Ćepulić
- Marko Lilić (ORCID: https://orcid.org/0000-0003-4017-4622)
Institutions
- University Hospital Centre Zagreb (HR)
- University of Mostar (BA)
- University of Zagreb (HR)
- University of Applied Health Sciences (HR)
- Opća Bolnica Varaždin (HR)
- University of Osijek (HR)
Publication Details
- Journal
- Transfusion
- Published
- 2025-05-27
- DOI
- https://doi.org/10.1111/trf.18294
- Citations
- 2
- Primary Topic
- Blood groups and transfusion
- Type
- article
- Field-Weighted Citation Impact
- 3.54