Immunogenicity of Neoantigens in Colorectal Cancer: Potential Influence of Tumor Mutation Burden, Stages, and Metastasis
In CRC, highly immunogenic neoantigens may be associated with tumor mutational burden and metastasis, whereas common neoantigens in primary and metastatic lesions may be immunologically suppressed.
Authors
- KOJI TAMADA
- Tatsuya Ioka (ORCID: https://orcid.org/0000-0002-0197-1832)
- Ryouichi Tsunedomi (ORCID: https://orcid.org/0000-0003-4251-1936)
- Yuki Nakagami (ORCID: https://orcid.org/0009-0001-0050-3439)
- Hidenori Takahashi (ORCID: https://orcid.org/0000-0001-7872-1519)
- Shoichi Hazama (ORCID: https://orcid.org/0000-0002-5239-8570)
- Hiroaki Nagano (ORCID: https://orcid.org/0000-0002-7074-3315)
- Shinobu Tomochika
- Xiaowei Yu (ORCID: https://orcid.org/0000-0001-8313-2559)
- Michihisa Iida (ORCID: https://orcid.org/0000-0002-3081-7148)
Institutions
- Yamaguchi University (JP)
- Yamaguchi University Hospital (JP)
Publication Details
- Journal
- Anticancer Research
- Published
- 2025-05-27
- DOI
- https://doi.org/10.21873/anticanres.17611
- Primary Topic
- Immunotherapy and Immune Responses
- Type
- article
- Field-Weighted Citation Impact
- 0.00