Hydrocortisone and Risk Factors for Kidney Replacement Therapy in Septic Shock
In this post hoc cohort study of patients with septic shock enrolled in a large RCT, intravenous hydrocortisone was associated with a reduced risk of new KRT requirement following randomization.
Authors
- Lachlan Donaldson
- John Myburgh (ORCID: https://orcid.org/0000-0003-4088-7016)
- Jeremy Cohen (ORCID: https://orcid.org/0000-0002-1356-8506)
- Dorrilyn Rajbhandari
- Anthony Devaux (ORCID: https://orcid.org/0000-0002-8862-4218)
- Balasubramanian Venkatesh
- Naomi E. Hammond (ORCID: https://orcid.org/0000-0002-6559-7747)
- Kyle White (ORCID: https://orcid.org/0000-0002-0129-8297)
- Rinaldo Bellomo
Institutions
- The University of Sydney (AU)
- Queensland University of Technology (AU)
- The University of Queensland (AU)
- The University of Melbourne (AU)
- Royal North Shore Hospital (AU)
- Wesley Hospital (AU)
- Austin Hospital (AU)
- UNSW Sydney (AU)
- Australian and New Zealand Intensive Care Society (AU)
- The George Institute for Global Health (AU)
- Northern Sydney Local Health District (AU)
- St George Hospital (AU)
- Monash University (AU)
Publication Details
- Journal
- JAMA Network Open
- Published
- 2025-05-27
- DOI
- https://doi.org/10.1001/jamanetworkopen.2025.12279
- Citations
- 8
- Primary Topic
- Sepsis Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 10.83
Funders
- Baxter Healthcare Corporation
- Medical Research Council
- National Health and Medical Research Council