Life-saving and Limb-saving in Case of Primary Cutaneous Mucormycosis of the Lower Limb

Mucormycosis is a rare but potentially lethal fungal infection that can affect any organ system, especially in immune-compromised individuals. Cutaneous manifestations comprise < 10% of cases of mucormycosis. The hallmark of mucormycosis is angioinvasion followed by thrombosis and necrosis of infected tissues. Here, we report a case of primary invasive cutaneous mucormycosis in a 52-year-old male with uncontrolled diabetes who presented with necrotising fasciitis of the right leg. Ulcer edge biopsy and special stain examination were consistent with invasive cutaneous mucormycosis. Timely antifungal initiation and wide local necrosectomy saved the life and limb of our patient.

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Publication Details

Journal
Kerala Surgical Journal
Published
2025-01-01
DOI
https://doi.org/10.4103/ksj.ksj_3_25
Primary Topic
Antifungal resistance and susceptibility
Type
article
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article

Life-saving and Limb-saving in Case of Primary Cutaneous Mucormycosis of the Lower Limb

S. L. Shafy Ali Khan, K. Jagan, A. Mohamad Safwan
Kerala Surgical Journal
Antifungal resistance and susceptibility
article

Life-saving and Limb-saving in Case of Primary Cutaneous Mucormycosis of the Lower Limb

S. L. Shafy Ali Khan, K. Jagan, A. Mohamad Safwan
article en

Abstract

Mucormycosis is a rare but potentially lethal fungal infection that can affect any organ system, especially in immune-compromised individuals. Cutaneous manifestations comprise < 10% of cases of mucormycosis. The hallmark of mucormycosis is angioinvasion followed by thrombosis and necrosis of infected tissues. Here, we report a case of primary invasive cutaneous mucormycosis in a 52-year-old male with uncontrolled diabetes who presented with necrotising fasciitis of the right leg. Ulcer edge biopsy and special stain examination were consistent with invasive cutaneous mucormycosis. Timely antifungal initiation and wide local necrosectomy saved the life and limb of our patient.

Kerala Surgical JournalVol. 31(1)
Almas Hospital (IN)
Openalex Percentile: Top 85%
Antifungal resistance and susceptibility
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