CA9-Positive Keloid Fibroblasts: Modulator of Local Inflammation Induced by the Hypoxic and Glycolysis-enhanced Microenvironment
Hypoxia, glycolysis, and acidosis sequencing may underlie keloid pathogenesis. CA9 may represent a mediator promoting local inflammation in keloids. This study provides insights into potential therapeutic molecular targets of keloids to effectively suppress prolonged inflammation and reduce the frequency of keloid recurrence.
Authors
- Guohua Zhao (ORCID: https://orcid.org/0000-0003-0593-9175)
- Xianglan Zhang (ORCID: https://orcid.org/0000-0001-5653-5969)
- Aihua Gao
- ZHENLONG ZHENG
- Mi Yeon Cho (ORCID: https://orcid.org/0000-0001-9676-6681)
- NA YEONG CHO
- Mi Ryung Roh (ORCID: https://orcid.org/0000-0002-6285-2490)
- Kee Yang Chung (ORCID: https://orcid.org/0000-0003-3257-0297)
- Haoran Xi
Institutions
- Yonsei University (KR)
- Severance Hospital (KR)
- Gangnam Severance Hospital (KR)
- Yonsei University College of Dentistry
Publication Details
- Journal
- Anticancer Research
- Published
- 2025-05-27
- DOI
- https://doi.org/10.21873/anticanres.17614
- Primary Topic
- Dermatologic Treatments and Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00