Antitumor Activity of<i>Ex Vivo</i>Expanded Tumor Antigen Priming Cytotoxic T Cells Against Malignant Melanoma
DCs pulsed with killed allogeneic melanoma cells effectively cross-prime cytotoxic T cells that specifically target the Melan-A antigen. Moreover, naive CD8<sup>+</sup> T cells primed by Melan-A-loaded DCs successfully killed malignant melanoma cells, highlighting a promising strategy for adoptive immunotherapy against melanoma.
Authors
- Ho Joo Yoon (ORCID: https://orcid.org/0000-0002-4645-4863)
- Y. Park
- Jong Gwon Choi
- Jong-Seok Kim (ORCID: https://orcid.org/0000-0002-4560-2553)
- D. Cho
Institutions
- Konyang University (KR)
Publication Details
- Journal
- Anticancer Research
- Published
- 2025-05-27
- DOI
- https://doi.org/10.21873/anticanres.17607
- Citations
- 2
- Primary Topic
- CAR-T cell therapy research
- Type
- article
- Field-Weighted Citation Impact
- 2.09