Aortic Non-coronary Cusp Perforation Following Methicillin-Sensitive Staphylococcus aureus (MSSA) Endocarditis

Isolated perforation of the aortic valve's noncoronary cusp (NCC) is an exceptionally rare but serious complication following bacterial endocarditis. Here we present a unique case of a 62-year-old male who developed an isolated NCC perforation after recovering from Methicillin-sensitive <i>Staphylococcus aureus</i> (MSSA) endocarditis. Despite successful antibiotic therapy, the patient experienced progressive cardiac symptoms, ultimately leading to the discovery of severe aortic insufficiency due to NCC perforation. This case underscores the importance of vigilant follow-up and the potential for late-onset complications in patients with a history of endocarditis.

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Publication Details

Journal
Cureus
Published
2025-05-27
DOI
https://doi.org/10.7759/cureus.84897
Primary Topic
Infective Endocarditis Diagnosis and Management
Type
article
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0.00
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article

Aortic Non-coronary Cusp Perforation Following Methicillin-Sensitive Staphylococcus aureus (MSSA) Endocarditis

Dhara Rana, Benjamin C. Silverman, Aobo Li, R. Elwyn Isaac et al.
Cureus
Infective Endocarditis Diagnosis and Management
article

Aortic Non-coronary Cusp Perforation Following Methicillin-Sensitive Staphylococcus aureus (MSSA) Endocarditis

Dhara Rana, Benjamin C. Silverman, Aobo Li, R. Elwyn Isaac, Vakula Atthota
article en

Abstract

Isolated perforation of the aortic valve's noncoronary cusp (NCC) is an exceptionally rare but serious complication following bacterial endocarditis. Here we present a unique case of a 62-year-old male who developed an isolated NCC perforation after recovering from Methicillin-sensitive <i>Staphylococcus aureus</i> (MSSA) endocarditis. Despite successful antibiotic therapy, the patient experienced progressive cardiac symptoms, ultimately leading to the discovery of severe aortic insufficiency due to NCC perforation. This case underscores the importance of vigilant follow-up and the potential for late-onset complications in patients with a history of endocarditis.

CureusVol. 17(5)
Inspira Medical Center Vineland (US), Vineland Research and Innovation Centre (CA), Rowan University (US)
Zero hunger
Openalex Percentile: Top 83%
Infective Endocarditis Diagnosis and Management
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Aortic Non-coronary Cusp Perforation Following Methicillin-Sensitive Staphylococcus aureus (MSSA) Endocarditis — Dhara Rana, Benjamin C. Silverman, et al. · Cureus (2025) | TGRS Research Map | TGRS