Comprehensive profiling of folates across polyglutamylation and one-carbon states
Our metabolomics approach tailored to folate polyglutamates reveals multiple layers of one-carbon metabolism organized by the lengths of polyglutamate tails in folates. Our analytical workflow is broadly applicable to folate profiling across various cell types to advance our knowledge of one-carbon metabolism as well as biotechnology and medicine.
Authors
- Sevcan Erşan (ORCID: https://orcid.org/0000-0002-5334-1955)
- Junyoung O. Park (ORCID: https://orcid.org/0000-0001-9869-8993)
- Yu Chen (ORCID: https://orcid.org/0009-0001-2693-1693)
Institutions
- University of California, Los Angeles (US)
Publication Details
- Journal
- Metabolomics
- Published
- 2025-05-26
- DOI
- https://doi.org/10.1007/s11306-025-02269-5
- Primary Topic
- Metabolomics and Mass Spectrometry Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Institute of General Medical Sciences