Risk of Pancreatic Cancer in Cystic Fibrosis and Cystic Fibrosis Transmembrane Conductance Regulator Germline Variants: A Retrospective Cohort Study

Patients with CF or CFTR gene variants had an almost 3-fold higher adjusted risk of PC than the general population after the age of 50 years. The risk may be further increased with a family history of PC.

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Publication Details

Journal
Clinical and Translational Gastroenterology
Published
2025-05-27
DOI
https://doi.org/10.14309/ctg.0000000000000857
Citations
2
Primary Topic
Cystic Fibrosis Research Advances
Type
article
Field-Weighted Citation Impact
3.04
Controls
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article

Risk of Pancreatic Cancer in Cystic Fibrosis and Cystic Fibrosis Transmembrane Conductance Regulator Germline Variants: A Retrospective Cohort Study

Bechien U. Wu, Tiffany Luong, Qiaoling Chen, Nikita Patel
2 citations
Clinical and Translational Gastroenterology
Cystic Fibrosis Research Advances
3.04
article

Risk of Pancreatic Cancer in Cystic Fibrosis and Cystic Fibrosis Transmembrane Conductance Regulator Germline Variants: A Retrospective Cohort Study

Bechien U. Wu, Tiffany Luong, Qiaoling Chen, Nikita Patel
article en
2 citations

Abstract

Patients with CF or CFTR gene variants had an almost 3-fold higher adjusted risk of PC than the general population after the age of 50 years. The risk may be further increased with a family history of PC.

Clinical and Translational GastroenterologyVol. 16(7)
Kaiser Permanente (US), Los Angeles Medical Center (US)
Good health and well-being
Openalex Percentile: Top 9%
Cystic Fibrosis Research Advances
3.04
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