Inter- and intra-observer variability of software quantified bowel motility measurements of small bowel Crohn’s disease: findings from the MOTILITY trial
Motility MRI is a novel biomarker of small bowel Crohn's disease activity. Currently, limited data on intra- and inter-observer variability exists. Motility MRI shows moderate to good inter- and intra-observer agreement. Intraclass correlation was 0.59-0.71 for experienced and inexperienced radiologists. Motility MRI is reproducible, supporting its utility as a biomarker of disease activity.
Authors
- Lindsay Rogers
- Eric Loveday (ORCID: https://orcid.org/0000-0001-6244-3163)
- Alex Menys (ORCID: https://orcid.org/0000-0001-6088-0730)
- Steve Halligan (ORCID: https://orcid.org/0000-0003-0632-5108)
- Naomi Sakai (ORCID: https://orcid.org/0000-0002-0008-5476)
- Stuart A. Taylor (ORCID: https://orcid.org/0000-0002-6765-8806)
- Edmund Godfrey (ORCID: https://orcid.org/0000-0002-4268-8494)
- Anisha Bhagwanani
- Darren Boone (ORCID: https://orcid.org/0000-0002-3178-9791)
- Nina Barratt
- Maria Dilawershah
- B Theis
- Nora Thoua
- Heather Fitzke (ORCID: https://orcid.org/0000-0003-4713-9985)
- Felix Kpodo
- Kamal Patel (ORCID: https://orcid.org/0000-0003-2611-4260)
- Lana Ward
- Ailsa L Hart (ORCID: https://orcid.org/0000-0002-7141-6076)
- Maryam Mohsin
- Klaartje Bel Kok (ORCID: https://orcid.org/0000-0002-5942-9149)
- Andrew Plumb (ORCID: https://orcid.org/0000-0003-1322-5113)
- Gauraang Bhatnagar (ORCID: https://orcid.org/0000-0001-6607-1117)
- James Franklin (ORCID: https://orcid.org/0000-0002-0316-3177)
- Sarah Langlands
- Felicia Onoviran
- Damian Tolan (ORCID: https://orcid.org/0000-0001-9895-9874)
- Konstantina Rosiou (ORCID: https://orcid.org/0000-0001-7260-1866)
- Roman Jastrub
- Tracy Foster
- Hannah Lambie
- Elen Thomson
- Anthony Higginson
- Maira Hameed (ORCID: https://orcid.org/0000-0002-6290-5695)
- Ilan Jacobs (ORCID: https://orcid.org/0000-0002-4705-1425)
- Emma Helbren
- Miles Parkes (ORCID: https://orcid.org/0000-0002-6467-0631)
- Kashfia Chowdhury (ORCID: https://orcid.org/0000-0002-8185-5152)
- Gordon W. Moran (ORCID: https://orcid.org/0000-0002-8906-6908)
- Stuart Bloom
- Harbir Sidhu (ORCID: https://orcid.org/0000-0003-3564-3383)
- Jaymin Patel (ORCID: https://orcid.org/0000-0001-6698-5365)
- Norin Ahmed (ORCID: https://orcid.org/0000-0001-8798-5217)
- Nicola Gibbons
- Simon P.L. Travis (ORCID: https://orcid.org/0000-0002-2690-4361)
- Helen Rafferty
- Sara McCartney (ORCID: https://orcid.org/0000-0003-2438-6086)
- Saiam Ahmed (ORCID: https://orcid.org/0000-0001-7543-5031)
- Safi Rahman
- Nishant Patodi
- Sue Philpott (ORCID: https://orcid.org/0000-0002-1019-5871)
- Shankar Kumar (ORCID: https://orcid.org/0000-0002-5945-8791)
- Biljana Brezina (ORCID: https://orcid.org/0000-0001-5060-5604)
- Yakup Kilic (ORCID: https://orcid.org/0000-0003-1319-9517)
- Peter D. Mooney (ORCID: https://orcid.org/0000-0002-6647-6728)
- Anmol Gangi (ORCID: https://orcid.org/0000-0001-6608-3847)
- Elizabeth Isaac (ORCID: https://orcid.org/0000-0002-4928-0870)
- Annamaria Wilce
- Anvi Wadke
- Amanda Cetroni
- Suzanne Roffe
- M. Joseph (ORCID: https://orcid.org/0000-0003-3809-405X)
- Arun Gupta (ORCID: https://orcid.org/0000-0003-0311-4284)
- Jaspreet Kaur (ORCID: https://orcid.org/0000-0002-2883-9241)
- Rachel Baldwin‐Cleland (ORCID: https://orcid.org/0000-0002-8736-2711)
- Charlotte Robinson (ORCID: https://orcid.org/0000-0003-4474-993X)
- Steven R. Williams
- Bessie Cipriano
- Tariq Ahmad
- Kamini Patel
- Jude Holmes
- Judith Holmes
- Anisha Patel
- Rachel Hyland
- Richard Pollok (ORCID: https://orcid.org/0000-0003-4278-3720)
- Teresita Beeston
- Abi Seward
- J Choudhury (ORCID: https://orcid.org/0009-0005-4141-5039)
- Robert Przemiosolo
- Javen Ramsami
- Fardowsa Ahmed-Timms
- Uday Bannur Chikkeragowda
Institutions
- University College Hospital (GB)
- North Bristol NHS Trust (GB)
- Nottingham University Hospitals NHS Trust (GB)
- University College London Hospitals NHS Foundation Trust (GB)
- University of Nottingham (GB)
- University of Hull (GB)
- Barts Health NHS Trust (GB)
- Royal Devon & Exeter NHS Foundation Trust (GB)
- Hull University Teaching Hospitals NHS Trust (GB)
- Western General Hospital (GB)
- Frenchay Hospital (GB)
- St George’s University Hospitals NHS Foundation Trust (GB)
- Frimley Park Hospital (GB)
- St James's University Hospital (GB)
- Royal Berkshire NHS Foundation Trust (GB)
- Epsom and St Helier University Hospitals NHS Trust (GB)
- University of Oxford (GB)
- Portsmouth Hospitals NHS Trust (GB)
- St. Mark's Hospital (US)
- Homerton University Hospital NHS Foundation Trust (GB)
- Nottingham Biomedical Research Centre (GB)
- Addenbrooke's Hospital (GB)
- St Mark's Hospital (GB)
- Comprehensive Clinical Trials (US)
- University College London (GB)
- Bournemouth University (GB)
Publication Details
- Journal
- Insights into Imaging
- Published
- 2025-05-27
- DOI
- https://doi.org/10.1186/s13244-025-01978-8
- Citations
- 2
- Primary Topic
- Inflammatory Bowel Disease
- Type
- article
- Field-Weighted Citation Impact
- 3.63
Funders
- National Institute for Health and Care Research
- University College London Hospitals NHS Foundation Trust
- Efficacy and Mechanism Evaluation Programme