Inter- and intra-observer variability of software quantified bowel motility measurements of small bowel Crohn’s disease: findings from the MOTILITY trial

Motility MRI is a novel biomarker of small bowel Crohn's disease activity. Currently, limited data on intra- and inter-observer variability exists. Motility MRI shows moderate to good inter- and intra-observer agreement. Intraclass correlation was 0.59-0.71 for experienced and inexperienced radiologists. Motility MRI is reproducible, supporting its utility as a biomarker of disease activity.

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Publication Details

Journal
Insights into Imaging
Published
2025-05-27
DOI
https://doi.org/10.1186/s13244-025-01978-8
Citations
2
Primary Topic
Inflammatory Bowel Disease
Type
article
Field-Weighted Citation Impact
3.63

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article

Inter- and intra-observer variability of software quantified bowel motility measurements of small bowel Crohn’s disease: findings from the MOTILITY trial

Lindsay Rogers, Eric Loveday, Alex Menys, Steve Halligan et al.
2 citations
Insights into Imaging
Inflammatory Bowel Disease
3.63
article

Inter- and intra-observer variability of software quantified bowel motility measurements of small bowel Crohn’s disease: findings from the MOTILITY trial

Lindsay Rogers, Eric Loveday, Alex Menys, Steve Halligan, Naomi Sakai, Stuart A. Taylor, Edmund Godfrey, Anisha Bhagwanani, Darren Boone, Nina Barratt, Maria Dilawershah, B Theis, Nora Thoua, Heather Fitzke, Felix Kpodo, Kamal Patel, Lana Ward, Ailsa L Hart, Maryam Mohsin, Klaartje Bel Kok, Andrew Plumb, Gauraang Bhatnagar, James Franklin, Sarah Langlands, Felicia Onoviran, Damian Tolan, Konstantina Rosiou, Roman Jastrub, Tracy Foster, Hannah Lambie, Elen Thomson, Anthony Higginson, Maira Hameed, Ilan Jacobs, Emma Helbren, Miles Parkes, Kashfia Chowdhury, Gordon W. Moran, Stuart Bloom, Harbir Sidhu, Jaymin Patel, Norin Ahmed, Nicola Gibbons, Simon P.L. Travis, Helen Rafferty, Sara McCartney, Saiam Ahmed, Safi Rahman, Nishant Patodi, Sue Philpott, Shankar Kumar, Biljana Brezina, Yakup Kilic, Peter D. Mooney, Anmol Gangi, Elizabeth Isaac, Annamaria Wilce, Anvi Wadke, Amanda Cetroni, Suzanne Roffe, M. Joseph, Arun Gupta, Jaspreet Kaur, Rachel Baldwin‐Cleland, Charlotte Robinson, Steven R. Williams, Bessie Cipriano, Tariq Ahmad, Kamini Patel, Jude Holmes, Judith Holmes, Anisha Patel, Rachel Hyland, Richard Pollok, Teresita Beeston, Abi Seward, J Choudhury, Robert Przemiosolo, Javen Ramsami, Fardowsa Ahmed-Timms, Uday Bannur Chikkeragowda
article en
2 citations

Abstract

Motility MRI is a novel biomarker of small bowel Crohn's disease activity. Currently, limited data on intra- and inter-observer variability exists. Motility MRI shows moderate to good inter- and intra-observer agreement. Intraclass correlation was 0.59-0.71 for experienced and inexperienced radiologists. Motility MRI is reproducible, supporting its utility as a biomarker of disease activity.

Insights into ImagingVol. 16(1)
University College Hospital (GB), North Bristol NHS Trust (GB), Nottingham University Hospitals NHS Trust (GB), University College London Hospitals NHS Foundation Trust (GB), University of Nottingham (GB), University of Hull (GB), Barts Health NHS Trust (GB), Royal Devon & Exeter NHS Foundation Trust (GB), Hull University Teaching Hospitals NHS Trust (GB), Western General Hospital (GB), Frenchay Hospital (GB), St George’s University Hospitals NHS Foundation Trust (GB), Frimley Park Hospital (GB), St James's University Hospital (GB), Royal Berkshire NHS Foundation Trust (GB), Epsom and St Helier University Hospitals NHS Trust (GB), University of Oxford (GB), Portsmouth Hospitals NHS Trust (GB), St. Mark's Hospital (US), Homerton University Hospital NHS Foundation Trust (GB), Nottingham Biomedical Research Centre (GB), Addenbrooke's Hospital (GB), St Mark's Hospital (GB), Comprehensive Clinical Trials (US), University College London (GB), Bournemouth University (GB)
National Institute for Health and Care Research, University College London Hospitals NHS Foundation Trust, Efficacy and Mechanism Evaluation Programme
Openalex Percentile: Top 8%
Inflammatory Bowel Disease
3.63
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