The burden and trends of gastric cancer from 1990 to 2021 in China and globally: a cross-sectional study

Over the past three decades, significant progress has been made in reducing the burden of gastric cancer in China and globally, with declining incidence and mortality rates. These trends are expected to continue in the coming years. However, low-and middle-income countries have seen more limited reductions, with some regions even experiencing increasing burdens. The findings underscore the need for enhanced public health policies focused on preventing <i>Helicobacter pylori</i> infections, promoting healthy dietary and lifestyle changes, and expanding the coverage of early screening programs. This study provides critical evidence to support the optimization of global and regional gastric cancer prevention and control strategies.