Causal Association Between Genetically Predicted Circulating Metabolites and Pressure Ulcers: A Two-Sample Mendelian Randomization Study
This study highlights significant causal relationships between circulating metabolites and PU risk. The identification of the spermidine to choline ratio as a risk factor and homostachydrine levels as a protective factor suggests potential metabolic targets for PU prevention and treatment.
Authors
- Peng Miao (ORCID: https://orcid.org/0000-0003-3993-4778)
- Xiaoli Hu (ORCID: https://orcid.org/0009-0009-3843-7551)
- Yue Zhang (ORCID: https://orcid.org/0000-0003-2317-062X)
- Yuchao Wu
Institutions
- Affiliated Hospital of Southwest Medical University (CN)
Publication Details
- Journal
- Journal of Inflammation Research
- Published
- 2025-05-01
- DOI
- https://doi.org/10.2147/jir.s503370
- Primary Topic
- Adipose Tissue and Metabolism
- Type
- article
- Field-Weighted Citation Impact
- 0.00