Durvalumab after concurrent chemoradiotherapy for sensitizing epidermal growth factor receptor-mutant stage III non-small cell lung cancer: A Japanese Real-World data analysis

Durvalumab administration following CCRT prolongs PFS in patients with locally advanced EGFR-mutant NSCLC. Durvalumab can be safely administered if the timing of subsequent osimertinib is carefully managed.

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Publication Details

Journal
Lung Cancer
Published
2025-05-27
DOI
https://doi.org/10.1016/j.lungcan.2025.108597
Primary Topic
Lung Cancer Treatments and Mutations
Type
article
Field-Weighted Citation Impact
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article

Durvalumab after concurrent chemoradiotherapy for sensitizing epidermal growth factor receptor-mutant stage III non-small cell lung cancer: A Japanese Real-World data analysis

Ayako Takigami, Satoshi Takahashi, Makoto Maemondo, Gen Kida et al.
3 links
Lung Cancer
Lung Cancer Treatments and Mutations
article

Durvalumab after concurrent chemoradiotherapy for sensitizing epidermal growth factor receptor-mutant stage III non-small cell lung cancer: A Japanese Real-World data analysis

Ayako Takigami, Satoshi Takahashi, Makoto Maemondo, Gen Kida, Eisaku Miyauchi, Ken Masuda, Akira Nakao, Hajime Kikuchi, Motohiro Tamiya, Kazuhiro Nishiyama, Yukari Tsubata, Toshiya Fujisaki, Yoshiaki Nagai, Daisuke Arai, Satoshi Watanabe, Yu Miura, Hironori Ashinuma, Ken Masubuchi, Satoshi Morita, Taichi Miyawaki, Kana Watanabe
article en

Abstract

Durvalumab administration following CCRT prolongs PFS in patients with locally advanced EGFR-mutant NSCLC. Durvalumab can be safely administered if the timing of subsequent osimertinib is carefully managed.

Lung CancerVol. 205
Jichi Medical University (JP), St. Marianna University School of Medicine (JP), Shimane University (JP), Kyoto University (JP), Juntendo University (JP), Fukuoka University Hospital (JP), Tohoku University Hospital (JP), Tachikawa Medical Center (JP), Miyagi Prefectural Hospital Organization (JP), Hiroshima Prefectural Hospital (JP), Tokyo Medical University Hospital (JP), Obihiro Kosei General Hospital (JP), Chiba Cancer Center (JP), Saiseikai Utsunomiya hospital (JP), Saitama Cancer Center (JP), Osaka International Cancer Institute (JP), Hyogo Prefectural Cancer Center (JP), Jichi Medical University Saitama Medical Center (JP), Niigata University (JP), Saitama Medical University (JP)
Good health and well-being
Openalex Percentile: Top 81%
Lung Cancer Treatments and Mutations
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Durvalumab after concurrent chemoradiotherapy for sensitizing epidermal growth factor receptor-mutant stage III non-small cell lung cancer: A Japanese Real-World data analysis — Ayako Takigami, Satoshi Takahashi, et al. · Lung Cancer (2025) | TGRS Research Map | TGRS