Assessment of peripheral nerve injury with impedance neurography: a pilot <i>in silico</i> study

Abstract Peripheral nerve injuries (PNIs) present a significant clinical challenge, with current diagnostic tools often falling short in guiding optimal surgical management. Traditional intraoperative techniques, such as recording nerve action potentials, are rarely utilized due to technical limitations including poor signal quality, artifact interference, and lengthy procedure times. To address this gap, we propose electrical impedance neurography (ING), a technology for real-time, intraoperative assessment of nerve health. In this pilot simulation study, we aim to evaluate the capability of ING to detect the location and quantify nerve injury severity using PNI. ING technology could assist intraoperative nerve assessment by providing insights into nerve integrity, improving surgical outcomes, and ultimately enhancing recovery for patients with traumatic nerve injuries.