Impedance cardiography assessment during body immersion in a high concentrated water solution of magnesium chloride simulating space microgravity: a pilot study

Abstract In 14 healthy subjects (9 males and 5 females, 32±15 years) a beat-by-beat cardiodynamic profile was acquired with impedance cardiography during 10 minutes while lying supine and relaxed in a bed and then in a bath tub with a high concentration of MgCl 2 reaching density 1/3 times more than sea. While in the tub, an increase in ventricular preload index (+47%) with reduction in contractility (-17%) and arterial pressure (-5%) occurred like as in space flights. So this method could be seen as a new way to simulating space fly at ground.

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Publication Details

Journal
Journal of Physics Conference Series
Published
2025-05-01
DOI
https://doi.org/10.1088/1742-6596/3014/1/012006
Primary Topic
Spaceflight effects on biology
Type
article
Field-Weighted Citation Impact
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article

Impedance cardiography assessment during body immersion in a high concentrated water solution of magnesium chloride simulating space microgravity: a pilot study

Fernanda Velluzzi, Maurizio Ruggiu, F Pili, Andrea Manuello Bertetto et al.
Journal of Physics Conference Series
Spaceflight effects on biology
article

Impedance cardiography assessment during body immersion in a high concentrated water solution of magnesium chloride simulating space microgravity: a pilot study

Fernanda Velluzzi, Maurizio Ruggiu, F Pili, Andrea Manuello Bertetto, Alberto Concu, Filippo Tocco, A. Fois, AH Dell’Osa, S. Melis, A Cerina, G Bellomi, M Palmas
article en

Abstract

Abstract In 14 healthy subjects (9 males and 5 females, 32±15 years) a beat-by-beat cardiodynamic profile was acquired with impedance cardiography during 10 minutes while lying supine and relaxed in a bed and then in a bath tub with a high concentration of MgCl 2 reaching density 1/3 times more than sea. While in the tub, an increase in ventricular preload index (+47%) with reduction in contractility (-17%) and arterial pressure (-5%) occurred like as in space flights. So this method could be seen as a new way to simulating space fly at ground.

Journal of Physics Conference SeriesVol. 3014(1)
University of Cagliari (IT), Politecnico di Torino (IT), Mulago Hospital (UG), Ministerio de Educación Cultura y Deporte (ES), Institute for Biomedicine (IT)
Openalex Percentile: Top 85%
Spaceflight effects on biology
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Impedance cardiography assessment during body immersion in a high concentrated water solution of magnesium chloride simulating space microgravity: a pilot study — Fernanda Velluzzi, Maurizio Ruggiu, et al. · Journal of Physics Conference Series (2025) | TGRS Research Map | TGRS