Clinical and economic effectiveness of Schroth therapy in adolescent idiopathic scoliosis: insights from a machine learning- and active learning-based real-world study

Exercise-based therapy, combined with ML and AL techniques, appears to be a clinically effective and economically sustainable intervention for AIS management. ML models identified important predictors overlooked by classical methods, particularly highlighting the importance of treatment duration. These findings may inform evidence-based strategies for integrating personalized, data-driven approaches into conservative scoliosis treatment protocols and optimizing musculoskeletal healthcare resource allocation.