Integrated in-silico design and in vivo validation of multi-epitope vaccines for norovirus
Both in silico and in vivo experimental findings suggest that the proposed pipeline and vaccine immunogens could serve as valuable theoretical guidance for the development of multi-epitope vaccines against NoVs.
Authors
- Tianyi Qiu (ORCID: https://orcid.org/0000-0003-2619-0298)
- Yiwen Wei (ORCID: https://orcid.org/0000-0002-8216-6156)
- Jiayi Shu (ORCID: https://orcid.org/0000-0002-3705-3259)
- Xuanyi Wang (ORCID: https://orcid.org/0000-0001-6398-9184)
- Jingxuan Qiu (ORCID: https://orcid.org/0000-0001-8420-4593)
- Dong Zhang (ORCID: https://orcid.org/0000-0001-8186-4692)
- Xin Wang (ORCID: https://orcid.org/0000-0002-2845-8510)
- Junting Xie
- Wenjing Zheng (ORCID: https://orcid.org/0000-0001-7658-7731)
- Yuxi Zhang (ORCID: https://orcid.org/0000-0001-5368-1346)
- Xiaochuan Luo (ORCID: https://orcid.org/0000-0001-6886-1649)
- Sijie Wang (ORCID: https://orcid.org/0000-0002-8525-1532)
Institutions
- Shanghai Medical College of Fudan University (CN)
- University of Shanghai for Science and Technology (CN)
- State Key Laboratory of Food Science and Technology (CN)
- Collaborative Innovation Center of Chemistry for Energy Materials (CN)
Publication Details
- Journal
- Virology Journal
- Published
- 2025-05-27
- DOI
- https://doi.org/10.1186/s12985-025-02796-6
- Citations
- 9
- Primary Topic
- Viral gastroenteritis research and epidemiology
- Type
- article
- Field-Weighted Citation Impact
- 12.57
Funders
- National Natural Science Foundation of China
- Fudan University
- National Key Research and Development Program of China