Randomized Trial of Lung and Diaphragm Protective Ventilation in Children
A lung and diaphragm protective ventilation strategy using a CDS tool during the acute phase of ventilation resulted in a shorter length of weaning than usual care. Phase III trials in mechanically ventilated patients are warranted. (Funded by the National Institutes of Health and others; ClinicalTrials.gov number, NCT03266016.).
Authors
- Wendy Jean Mack (ORCID: https://orcid.org/0000-0002-2474-7921)
- D. Bornstein
- Martha A. Q. Curley (ORCID: https://orcid.org/0000-0001-5228-6694)
- D. Baron
- A. Armenta-Quiroz
- Marsha Elkunovich
- Robinder G. Khemani (ORCID: https://orcid.org/0000-0002-5815-0314)
- Justin Hotz
- Shilpa Shah (ORCID: https://orcid.org/0000-0003-1576-206X)
- Margaret J. Klein (ORCID: https://orcid.org/0000-0001-9783-7648)
- Lara P. Nelson (ORCID: https://orcid.org/0000-0001-8640-5639)
- J. Bonilla-Cartagena
- Anoopindar Bhalla (ORCID: https://orcid.org/0000-0002-1244-2442)
- Fernando Beltramo
- Timothy Deakers
- Kristen Kohler
- Patrick A. Ross (ORCID: https://orcid.org/0000-0002-2748-555X)
- Daniel Chang (ORCID: https://orcid.org/0000-0001-7810-2371)
- Christopher J. L. Newth
- Erin Smith
- Anil Suresh
- Jeni Kwok
- Kennedy Vu
Institutions
- University of Southern California (US)
- Children's Hospital of Los Angeles (US)
- University of Pennsylvania (US)
Publication Details
- Journal
- NEJM Evidence
- Published
- 2025-05-27
- DOI
- https://doi.org/10.1056/evidoa2400360
- Citations
- 8
- Primary Topic
- Respiratory Support and Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 12.15