Antiviral potential of proton-type zeolite
This study reports the potent antiviral ability of proton-type zeolites without the aid of any metal cations. Antiviral activities of zeolites with different topologies and chemical compositions are investigated using M13 phage and influenza virus. Proton-type zeolites exhibit excellent antiviral activity, equivalent to 99% inactivated. Antiviral tests using a centricon device suggest that direct contact of viruses on the external surface of zeolites is required to inactivate the viruses. This discovery is of importance in an interdisciplinary research field covering both zeolite science and virological science and shed light on the possibility of the development of low-cost and environmentally friendly antiviral zeolites.
Authors
- Koichi Sato (ORCID: https://orcid.org/0000-0001-5021-4988)
- Takeshi Ichinohe (ORCID: https://orcid.org/0000-0002-6376-2841)
- Makoto Nakakido (ORCID: https://orcid.org/0000-0003-0328-9914)
- Tatsuya Okubo (ORCID: https://orcid.org/0000-0002-1681-0193)
- Nobuhiro Miyamae
- Seiichi Ohta (ORCID: https://orcid.org/0000-0002-4775-8199)
- Kenta Iyoki (ORCID: https://orcid.org/0000-0002-1111-7111)
- Toru Wakihara (ORCID: https://orcid.org/0000-0002-3916-3849)
- Yuka Kimura (ORCID: https://orcid.org/0000-0001-9072-9329)
- Kouhei Tsumoto (ORCID: https://orcid.org/0000-0001-7643-5164)
- Yuki Egami
- Noriko Nakamura (ORCID: https://orcid.org/0000-0002-9086-2581)
- Masanori Takemoto (ORCID: https://orcid.org/0000-0002-3043-5676)
Institutions
- National Institute of Infectious Diseases (JP)
- Nippon Paint (Japan) (JP)
- The University of Tokyo (JP)
Publication Details
- Journal
- PLoS ONE
- Published
- 2025-05-27
- DOI
- https://doi.org/10.1371/journal.pone.0324484
- Primary Topic
- Bacteriophages and microbial interactions
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Japan Agency for Medical Research and Development
- New Energy and Industrial Technology Development Organization
- Japan Society for the Promotion of Science