Peripheral blood mitochondrial DNA copy number as a predictor of steatotic liver disease development: insights from epidemiological and experimental studies
Our findings suggest that reduced mtDNA-CN may contribute causally to SLD development and could serve as a convenient, noninvasive biomarker for early detection and risk assessment.
Authors
- Atsushi Teshigawara
- Yoshiki Tsuboi (ORCID: https://orcid.org/0000-0001-8145-3949)
- Takuya Wakasugi
- Eiji Munetsuna (ORCID: https://orcid.org/0000-0002-2151-5893)
- Koji Suzuki (ORCID: https://orcid.org/0000-0002-3235-9558)
- Genki Mizuno (ORCID: https://orcid.org/0000-0001-8052-5146)
- Nobutaka Ohgami (ORCID: https://orcid.org/0000-0002-3108-9090)
- Naohiro Ichino
- Koji Ohashi (ORCID: https://orcid.org/0000-0002-9666-026X)
- Yuji Hattori (ORCID: https://orcid.org/0000-0001-5060-0803)
- Mirai Yamazaki (ORCID: https://orcid.org/0000-0001-8170-9027)
- Hiroaki Ishikawa (ORCID: https://orcid.org/0000-0002-5295-2957)
- Ryosuke Fujii (ORCID: https://orcid.org/0000-0003-1730-2059)
- Itsuki Kageyama
- Keiko Sugimoto (ORCID: https://orcid.org/0000-0003-2422-5338)
- Yoshitaka Ando (ORCID: https://orcid.org/0000-0002-1213-8096)
- Keisuke Osakabe
- Hiroya Yamada
Institutions
- Fujita Health University (JP)
- Tokyo University of Technology (JP)
- Fujita Health University Hospital (JP)
- Azabu University (JP)
Publication Details
- Journal
- Environmental Health and Preventive Medicine
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1265/ehpm.25-00025
- Citations
- 2
- Primary Topic
- Liver Disease Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 2.71
Funders
- Japan Society for the Promotion of Science