A comprehensive case report of kimura’s disease: diagnosis and treatment insights

Kimura's disease is a rare chronic inflammatory disorder primarily affecting the head and neck region. We present a case of a 35-year-old male patient with swelling over the right preauricular region and right eyebrow for 5 months. The patient's blood investigations revealed elevated eosinophil count, increased absolute eosinophil count, and significantly elevated serum IgE levels. Ultrasonography suggested lipomatosis, while fine-needle aspiration cytology (FNAC) was inconclusive. Excisional biopsy of the swellings confirmed the diagnosis of Kimura's disease based on histopathological findings of hyperplastic lymphoid follicles with micro abscesses. The patient was initiated on intravenous dexamethasone, resulting in a reduction in swelling size and a subsequent decrease in serum IgE levels and eosinophil count. This case report highlights the clinical presentation, diagnostic challenges, and therapeutic response of Kimura's disease.