Cellular and molecular mechanisms of alpha lipoic acid’s protective effects against diclofenac-induced hepatorenal toxicity
These findings suggested potential therapeutic benefits for ALA in mitigating DIC-induced hepatorenal toxicity through its anti-inflammatory, antioxidant and Nrf2-mediating effects. Future investigations are warranted to explore the synergistic interactions and multiomics mechanisms.
Authors
- Bardes B. Hassan (ORCID: https://orcid.org/0000-0003-0026-5239)
- Reham M. Abd‐Elsalam (ORCID: https://orcid.org/0000-0002-8697-1232)
- Sherif H. Elmosalamy (ORCID: https://orcid.org/0000-0002-9875-5262)
- Neven H. Hassan (ORCID: https://orcid.org/0000-0003-1110-4289)
- Shymaa A. El Badawy (ORCID: https://orcid.org/0000-0001-9439-2364)
- Hanan A. Ogaly (ORCID: https://orcid.org/0000-0002-0480-5127)
- Fatimah A. M. Al‐Zahrani (ORCID: https://orcid.org/0000-0002-7413-9115)
- Chun Guang Li (ORCID: https://orcid.org/0000-0002-7789-2209)
- Muhammad A. Alsherbiny (ORCID: https://orcid.org/0000-0001-9337-2441)
- Gehan Othman (ORCID: https://orcid.org/0000-0001-8470-0079)
Institutions
- Cairo University (EG)
- Western Sydney University (AU)
- King Khalid University (SA)
Publication Details
- Journal
- Journal of Veterinary Research
- Published
- 2025-05-23
- DOI
- https://doi.org/10.2478/jvetres-2025-0029
- Primary Topic
- Biochemical Acid Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00