Effect of switching from prior Nucleos(t)ide Analogue(s) to Tenofovir alafenamide on lipid profile and cardiovascular risk in patients with Chronic Hepatitis B
Significant increase in LDL-c and total cholesterol after switching to TAF were observed only in patients with prior TDF, but not in those with prior ETV or LAM. Careful monitoring of lipids after the switch may not be universally needed. Data regarding long-term cardiovascular outcomes are warrant.
Authors
- Pimsiri Sripongpun (ORCID: https://orcid.org/0000-0003-0007-8214)
- Naichaya Chamroonkul (ORCID: https://orcid.org/0000-0002-5753-7939)
- Teerha Piratvisuth (ORCID: https://orcid.org/0000-0002-5249-9208)
- Apichat Kaewdech (ORCID: https://orcid.org/0000-0002-4058-5977)
- Witchayaporn Praguylertluck
Institutions
- Prince of Songkla University (TH)
- Songklanagarind Hospital (TH)
Publication Details
- Journal
- PLoS ONE
- Published
- 2025-05-27
- DOI
- https://doi.org/10.1371/journal.pone.0324897
- Primary Topic
- Hepatitis C virus research
- Type
- article
- Field-Weighted Citation Impact
- 0.00