Eligibility and GDMT up-titration success in heart failure: A real-world assessment
In this real-world study, 75% of patients with chronic severe HFrEF are eligible for GDMT up-titration towards target dosages. The clinical profile concept of the HFA might be adapted, as most classifiable patients can be up-titrated, and most severe patients are missed by the classification.
Authors
- Christian Hengstenberg (ORCID: https://orcid.org/0000-0002-8284-2994)
- Philipp Emanuel Bartko (ORCID: https://orcid.org/0000-0001-9061-4839)
- Georg Spinka (ORCID: https://orcid.org/0000-0002-8029-6491)
- Noémi Pávó (ORCID: https://orcid.org/0000-0003-3377-4507)
- Henrike Arfsten (ORCID: https://orcid.org/0000-0002-5836-7759)
- Michaela Stadler (ORCID: https://orcid.org/0009-0006-2644-2474)
- Martin Hülsmann (ORCID: https://orcid.org/0000-0001-7944-7363)
- Gregor Heitzinger (ORCID: https://orcid.org/0000-0003-2094-0414)
- Anush Barkhudaryan (ORCID: https://orcid.org/0000-0001-5308-4832)
- Annika Weidenhammer (ORCID: https://orcid.org/0009-0008-3250-0364)
- Guido Strunk (ORCID: https://orcid.org/0000-0002-0607-5105)
- Noel G. Panagiotides (ORCID: https://orcid.org/0000-0002-5246-8241)
- Clemens Partsch
- Georg Goliasch
- Suriya Prausmüller (ORCID: https://orcid.org/0000-0002-6937-7979)
Institutions
- Complexity Science Hub (AT)
- Yerevan State Medical University (AM)
- Medical University of Vienna (AT)
Publication Details
- Journal
- PLoS ONE
- Published
- 2025-05-27
- DOI
- https://doi.org/10.1371/journal.pone.0323952
- Citations
- 3
- Primary Topic
- Heart Failure Treatment and Management
- Type
- article
- Field-Weighted Citation Impact
- 4.16