Characterization of antimicrobial resistance among Proteus mirabilis isolates from catheter-associated urinary tract infections and non-catheter-associated urinary tract infections in Egypt

The high frequency of MDR P. mirabilis strains isolated from UTIs in Egypt, particularly among catheterized patients, is a major concern, especially with disseminating class 1 and 2 integrons among isolates. The study also highlights the decreased susceptibility to sulphonamides, 3rd generation cephalosporins, and imipenem, commonly used to treat UTIs. Increased dissemination of ESBL-producing Proteus isolates among CAUTIs complicates their treatments. This important pathogen deserves more attention in the future for a better understanding of resistance mechanisms and the dissemination potential of resistant strains.