Relative fat mass and risk of metabolic dysfunction associated steatotic liver disease and severe hepatic steatosis in U.S. adults: analysis of NHANES 2017–2020 data
Our results demonstrated a positive nonlinear relationship between RFM and the prevalence of MASLD and SHS, with a threshold effect. Lower RFM levels are associated with lower odds of MASLD and SHS. These findings suggest that RFM may serve as a simple, cost-effective tool for identifying individuals at increased odds of NAFLD and SHS in the general population.
Authors
- Pei Yang (ORCID: https://orcid.org/0009-0009-1036-5525)
- Zhaohui Hu (ORCID: https://orcid.org/0000-0003-1124-680X)
- Sirui Chen (ORCID: https://orcid.org/0000-0001-7740-508X)
- Xintao Zeng
- Wei He (ORCID: https://orcid.org/0009-0004-3932-3859)
- Xi Chen (ORCID: https://orcid.org/0000-0002-6526-3018)
- Jianjun Wang
- Xianfu Cai
- Decai Wang (ORCID: https://orcid.org/0000-0003-2583-5584)
- Yonghai Peng
Institutions
- University of Electronic Science and Technology of China (CN)
- Mianyang Central Hospital (CN)
Publication Details
- Journal
- BMC Gastroenterology
- Published
- 2025-05-27
- DOI
- https://doi.org/10.1186/s12876-025-04006-7
- Citations
- 3
- Primary Topic
- Liver Disease Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 4.06
Funders
- National Natural Science Foundation of China
- Health Commission of Sichuan Province