Grain-sized moxibustion activates dendritic cells to enhance the antitumor immunity of cancer vaccines
Both gM and β-blockers enhance cancer vaccine efficacy through β-adrenergic suppression and maturation of DC. These findings mechanistically bridge TCM's fu zheng qu xie strategy with modern immunotherapy, positioning β-adrenergic modulation as a convergent target for traditional and pharmacological interventions.
Authors
- Huangan Wu (ORCID: https://orcid.org/0000-0003-1725-6881)
- Chenyuan Gong (ORCID: https://orcid.org/0009-0001-2268-9692)
- Weiming Shen (ORCID: https://orcid.org/0000-0001-5204-7992)
- Jiaojiao Luo (ORCID: https://orcid.org/0009-0006-4116-4855)
- Lixin Wang (ORCID: https://orcid.org/0000-0002-5402-8557)
- Shiguo Zhu (ORCID: https://orcid.org/0000-0002-1551-5221)
- Chao Yao (ORCID: https://orcid.org/0000-0001-9374-2510)
- Fang Cheng (ORCID: https://orcid.org/0000-0002-7978-4420)
- Chen Zhao (ORCID: https://orcid.org/0009-0005-2510-3174)
- Dan Hu (ORCID: https://orcid.org/0000-0002-5396-1230)
Institutions
- Renji Hospital (CN)
Publication Details
- Journal
- Chinese Medicine
- Published
- 2025-05-27
- DOI
- https://doi.org/10.1186/s13020-025-01134-w
- Citations
- 1
- Primary Topic
- Acupuncture Treatment Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 2.38
Funders
- Natural Science Foundation of Shanghai
- National Natural Science Foundation of China